Overview
Liquid chromatography (LC) separates compounds in solution using a liquid mobile phase and a stationary phase inside a column. LC systems range from analytical HPLC/UHPLC used for high-resolution separations to preparative units for larger-scale purification. Typical components include a pump, injector, column, detector and data system. Buyers choose systems by throughput, pressure rating, detector type and compatibility with solvents and sample types.
FAQ
What should I check when buying a used LC system?
Verify pump seals and vanes condition, check detector lamp hours (UV/PDA), inspect injector and column history, confirm software licensing and backups, and request maintenance and calibration records.
How should an LC be prepared for shipping?
Flush lines with compatible solvent, secure columns and fragile detectors, remove or lock flow cells where recommended, drain waste and pack with desiccant; use a carrier experienced in lab instruments.
What site requirements are needed before delivery?
Ensure stable bench or table, appropriate electrical supply and grounding, venting for solvent use, temperature control, and network access for data systems and software installation.
What routine maintenance keeps an LC reliable?
Regularly replace pump seals and filters, degasser maintenance, change detector lamps as needed, clean or replace columns per sample load, and run calibration standards to monitor performance.
Are software licenses and service contracts important?
Yes. Software licenses are required for instrument control and data processing; service contracts speed repairs and ensure parts availability, especially for pumps, detectors and critical electronics.